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Resources » Articles/Knowledge Sharing » Health »
Reactions from the sun-Photosensitivity, Phototoxic,Phototoxic induced by drugs,phytophotodermatitis
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Reactions from the sun
Photosensitivity
Photosensitivity reactions are those clinical pictures produced significant and abnormal, triggered or aggravated by exposure to light, usually solar. Unlike the fototoxia, the skin reacts in an exaggerated and not only played an increase in tone, but injuries are eczema, blister formation, etc ...
Phototoxic
Is the increased absorption of sunlight by making contact or medicines or chemicals, or sometimes by changes in the metabolism of the persons or in certain diseases. Injuries that occur are the same that produces the sun just appearing more intense and less exposure time.
Phototoxic induced by drugs
It is a cutaneous adverse reaction due to topical or systemic exposure of a drug and light. The chemicals may be responsible, in addition to pharmaceuticals, cosmetics and industrial products. The reaction can occur in any individual, is required and dose-dependent, and is essentially an exaggerated sunburn. It is more common than photo allergic reactions and may also appear at any age and any skin type. Eccematose reaction is not seen in phototoxic reactions.
The drugs involved are:
Nalidixic acid, amiodarone, captopril, clorotiacidas, etretinato, phenothiazines (chlorpromazine, prometacina, tioridacina, etc..), furosemide, griseofulvin, naproxen, pyrazinamide, piroxicam, or furocoumarines psoralens, sulfonamides, tetracyclines (especially doxycycline and dimetilclortetraciclina), and derivatives tar.
By eliminating the drug responsible, injuries yield.
Drug-induced photosensitivity
The drug present in the skin absorbs light (especially uv) photoproducts and a form that binds to proteins to form a complete antigen, which produces the allergic reaction. Injuries are e ccem, itchy blisters and exudation deaparición in areas exposed to sunlight, even if the exposure is extieden throughout the body. The photoallergy may persist for months or years despite the absence of contact with the substance responsible.
Causing general administration:
• Phenothiazines
• Sulphonamides
• FOR group
Topical administration of:
• Salicylanilides halogenated (deodorants and soaps)
• Paba and its derivatives (sunscreens)
• Cinnamate and benzophenone (sunscreen)
• Benzocaine
• Neomycin
• Musk perfume
• Tioureas in neoprene
Are used for diagnostic tests and epicutaneous fotopatch test, which is the reproduction of the application, a small dose of the suspect product in the skin for 24 hours and exposure to a uva lamp to different spectra to reproduce the lesion eczema.
Allergy photosensitive per plant (phytophotodermatitis)
It is a dermatitis caused by contact with plants and exposure to sunlight. It produces a phototoxic or photoallergic reaction, caused by substances photosensitising (furocoumarines), present in various plants.
Producing plants phytophotodermatitis
• Rutaca: lime, orange, bitter orange, lemon, bergamot, rough common.
• Umbelliferae: parsley, chervil, parsley, parsnips, fennel, dill, carrots,
• Composite: yarrow, chamomile and aquileo
• Cruciferae: mustard
• Moraceae: higueras (only leaf and stem)
• Ranunculaceas: ranunculus
• Rosaceae: agrimonia
• Legumes: peas
• Hiperaceas: st. John's wort
It can occur at any age and race. The professions most affected are gardening, horticulture, floriculture, agriculture, etc.. It is more common in summer. In the acute phase appears erythema, vesicles and blisters with itching, but without a chromate eczema.
There may be a residual pigmentation with artificial forms (lines, etc., depending on some work done on the outside). The lesions are distributed in areas of contact, especially in the arms and legs. Acute spontaneous eruption yields, but hyperpigmentation may persist for weeks.
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